Some researchers at Penn State in the 90s decided that using nuclear bombs for spacecraft propulsion (“Project Orion”) was not a crazy enough idea, and proposed igniting the nuclear bombs with antimatter. Each bomb would contain a microgram of antihydrogen to serve as a detonator, replacing the plutonium primary stage of a traditional design; the secondary stage could be fission or fusion.
Surprisingly there are actual advantages to this approach, although with the downsides that we currently have no technology for making enough antihydrogen, and that the fuel would detonate if looked at sternly.
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